General Structure Information
| PDB ID | 3owp |
| HGNC Gene Label(s) | PRKACA |
| Structure Name | human camp-dependent protein kinase in complex with an inhibitor |
| Resolution | 1.88Å |
| Reference | AUTH H.KOESTER,T.CRAAN,S.BRASS,A.HEINE,G.KLEBETITL FRAGMENT BASED DRUG DESIGN ON PKAREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 334 |
| Number Of SNVs | 56 |
| Number Of Permutations | 9526 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.077 |
| p-value | 0.516 |
COSMIC
| Number Of Residues | 334 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1197 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.143 |
| p-value | 0.6 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 56 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 27.0 |
| K Statistic | 0.326 |
| p-value | 0.277 |