General Structure Information
| PDB ID | 3owb |
| HGNC Gene Label(s) | HSP90AA1 |
| Structure Name | crystal structure of hsp90 with ver-49009 |
| Resolution | 2.05Å |
| Reference | AUTH M.BRUNCKO,S.K.TAHIR,X.SONG,J.CHEN,H.DING,J.R.HUTH,S.JIN,AUTH 2 R.A.JUDGE,D.J.MADAR,C.H.PARK,C.M.PARK,A.M.PETROS,C.TSE,AUTH 3 S.H.ROSENBERG,S.W.ELMORETITL N-ARYL-BENZIMIDAZOLONES AS NOVEL SMALL MOLECULE HSP90TITL 2 INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 20 7503 2010REFN ISSN 0960-894XPMID 21106457DOI 10.1016/J.BMCL.2010.10.010 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 207 |
| Number Of SNVs | 34 |
| Number Of Permutations | 10786 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.091 |
| p-value | 0.002 |
COSMIC
| Number Of Residues | 207 |
| Number Of SNVs | 3 |
| Number Of Permutations | 66 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.333 |
| p-value | 0.393 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
