General Structure Information
| PDB ID | 3ope |
| HGNC Gene Label(s) | ASH1L |
| Structure Name | structural basis of auto-inhibitory mechanism of histone methyltransferase |
| Resolution | 2.9Å |
| Reference | AUTH S.AN,K.J.YEO,Y.H.JEON,J.SONGTITL CRYSTAL STRUCTURE OF THE HUMAN HISTONE METHYLTRANSFERASETITL 2 ASH1L CATALYTIC DOMAIN AND ITS IMPLICATIONS FOR THETITL 3 REGULATORY MECHANISMREF J.BIOL.CHEM. V. 286 8369 2011REFN ISSN 0021-9258PMID 21239497DOI 10.1074/JBC.M110.203380 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 212 |
| Number Of SNVs | 23 |
| Number Of Permutations | 11927 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.166 |
| p-value | 0.005 |