General Structure Information
| PDB ID | 3o4o |
| HGNC Gene Label(s) | IL1R2 |
| Structure Name | crystal structure of an interleukin-1 receptor complex |
| Resolution | 3.3Å |
| Reference | AUTH D.L.WANG,S.Y.ZHANG,L.LI,X.LIU,K.R.MEI,X.Q.WANGTITL STRUCTURAL INSIGHTS INTO THE ASSEMBLY AND ACTIVATION OFTITL 2 IL-1BETA WITH ITS RECEPTORSREF NAT.IMMUNOL. V. 11 905 2010REFN ISSN 1529-2908PMID 20802483DOI 10.1038/NI.1925 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 316 |
| Number Of SNVs | 91 |
| Number Of Permutations | 23957 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.118 |
| p-value | 0.63 |
COSMIC
| Number Of Residues | 316 |
| Number Of SNVs | 8 |
| Number Of Permutations | 3077 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.25 |
| p-value | 0.342 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 91 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 29.0 |
| K Statistic | -0.154 |
| p-value | 0.802 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
