General Structure Information
| PDB ID | 3o4o |
| HGNC Gene Label(s) | IL1RAP |
| Structure Name | crystal structure of an interleukin-1 receptor complex |
| Resolution | 3.3Å |
| Reference | AUTH D.L.WANG,S.Y.ZHANG,L.LI,X.LIU,K.R.MEI,X.Q.WANGTITL STRUCTURAL INSIGHTS INTO THE ASSEMBLY AND ACTIVATION OFTITL 2 IL-1BETA WITH ITS RECEPTORSREF NAT.IMMUNOL. V. 11 905 2010REFN ISSN 1529-2908PMID 20802483DOI 10.1038/NI.1925 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 323 |
| Number Of SNVs | 64 |
| Number Of Permutations | 42843 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.143 |
| p-value | 0.374 |
COSMIC
| Number Of Residues | 323 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1319 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | 0.2 |
| p-value | 0.535 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.085 |
| p-value | 0.497 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
