General Structure Information
| PDB ID | 3nw0 |
| HGNC Gene Label(s) | NSMCE1 |
| Structure Name | crystal structure of mageg1 and nse1 complex |
| Resolution | 2.92Å |
| Reference | AUTH J.M.DOYLE,J.GAO,J.WANG,M.YANG,P.R.POTTSTITL MAGE-RING PROTEIN COMPLEXES COMPRISE A FAMILY OF E3TITL 2 UBIQUITIN LIGASES.REF MOL.CELL V. 39 963 2010REFN ISSN 1097-2765PMID 20864041DOI 10.1016/J.MOLCEL.2010.08.029 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 236 |
| Number Of SNVs | 61 |
| Number Of Permutations | 29210 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.016 |
| p-value | 0.791 |
COSMIC
| Number Of Residues | 236 |
| Number Of SNVs | 3 |
| Number Of Permutations | 199 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.667 |
| p-value | 0.652 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.298 |
| p-value | 0.799 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
