General Structure Information
| PDB ID | 3nvq |
| HGNC Gene Label(s) | PLXNC1 |
| Structure Name | molecular mechanism of guidance cue recognition |
| Resolution | 2.4Å |
| Reference | AUTH H.LIU,Z.S.JUO,A.H.SHIM,P.J.FOCIA,X.CHEN,K.C.GARCIA,X.HETITL STRUCTURAL BASIS OF SEMAPHORIN-PLEXIN RECOGNITION AND VIRALTITL 2 MIMICRY FROM SEMA7A AND A39R COMPLEXES WITH PLEXINC1.REF CELL(CAMBRIDGE,MASS.) V. 142 749 2010REFN ISSN 0092-8674PMID 20727575DOI 10.1016/J.CELL.2010.07.040 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 473 |
| Number Of SNVs | 77 |
| Number Of Permutations | 15645 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.02 |
| p-value | 0.675 |
COSMIC
| Number Of Residues | 473 |
| Number Of SNVs | 5 |
| Number Of Permutations | 977 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.2 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 77 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.086 |
| p-value | 0.546 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
