General Structure Information
| PDB ID | 3nr9 |
| HGNC Gene Label(s) | CLK2 |
| Structure Name | structure of human cdc2-like kinase 2 (clk2) |
| Resolution | 2.89Å |
| Reference | AUTH A.CHAIKUAD,P.SAVITSKY,T.KROJER,J.R.C.MUNIZ,AUTH 2 P.FILIPPAKOPOULOS,P.RELLOS,T.KEATES,O.FEDOROV,A.C.W.PIKE,AUTH 3 J.ESWARAN,G.BERRIDGE,C.PHILLIPS,Y.ZHANG,F.VON DELFT,AUTH 4 J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,S.KNAPP,AUTH 5 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL STRUCTURE OF HUMAN CDC2-LIKE KINASE 2 (CLK2)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 347 |
| Number Of SNVs | 49 |
| Number Of Permutations | 26931 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.145 |
| p-value | 0.046 |
COSMIC
| Number Of Residues | 347 |
| Number Of SNVs | 8 |
| Number Of Permutations | 1435 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.036 |
| p-value | 0.942 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 49 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.151 |
| p-value | 0.779 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
