General Structure Information
| PDB ID | 3m7p |
| HGNC Gene Label(s) | FN1 |
| Structure Name | fibronectin fragment |
| Resolution | 2.5Å |
| Reference | AUTH M.GRAILLE,M.PAGANO,T.ROSE,M.REBOUD RAVAUX,H.VAN TILBEURGHTITL ZINC INDUCES STRUCTURAL REORGANIZATION OF GELATIN BINDINGTITL 2 DOMAIN FROM HUMAN FIBRONECTIN AND AFFECTS COLLAGEN BINDINGREF STRUCTURE V. 18 710 2010REFN ISSN 0969-2126PMID 20541508DOI 10.1016/J.STR.2010.03.012 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 301 |
| Number Of SNVs | 79 |
| Number Of Permutations | 49114 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.077 |
| p-value | 0.355 |
COSMIC
| Number Of Residues | 301 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2161 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.067 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 79 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 31.0 |
| K Statistic | -0.221 |
| p-value | 0.773 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
