General Structure Information
| PDB ID | 3lyi |
| HGNC Gene Label(s) | BRD1 |
| Structure Name | pwwp domain of human bromodomain-containing protein 1 |
| Resolution | 2.1Å |
| Reference | AUTH H.WU,H.ZENG,R.LAM,W.TEMPEL,M.F.AMAYA,C.XU,L.DOMBROVSKI,AUTH 2 W.QIU,Y.WANG,J.MINTITL STRUCTURAL AND HISTONE BINDING ABILITY CHARACTERIZATIONS OFTITL 2 HUMAN PWWP DOMAINS.REF PLOS ONE V. 6 18919 2011REFN ESSN 1932-6203PMID 21720545DOI 10.1371/JOURNAL.PONE.0018919 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 120 |
| Number Of SNVs | 20 |
| Number Of Permutations | 5327 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.037 |
| p-value | 0.308 |
COSMIC
| Number Of Residues | 120 |
| Number Of SNVs | 3 |
| Number Of Permutations | 248 |
| Optimal Distance Threshold | 28.0 |
| K Statistic | 0.667 |
| p-value | 0.913 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 20 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | -0.153 |
| p-value | 0.943 |