General Structure Information
| PDB ID | 3lju |
| HGNC Gene Label(s) | ADAP1 |
| Structure Name | crystal structure of full length centaurin alpha-1 bound with the head group of pip3 |
| Resolution | 1.7Å |
| Reference | AUTH Y.TONG,W.TEMPEL,H.WANG,K.YAMADA,L.SHEN,G.A.SENISTERRA,AUTH 2 F.MACKENZIE,A.H.CHISHTI,H.W.PARKTITL PHOSPHORYLATION-INDEPENDENT DUAL-SITE BINDING OF THE FHATITL 2 DOMAIN OF KIF13 MEDIATES PHOSPHOINOSITIDE TRANSPORT VIATITL 3 CENTAURIN ALPHA1.REF PROC.NATL.ACAD.SCI.USA V. 107 20346 2010REFN ISSN 0027-8424PMID 21057110DOI 10.1073/PNAS.1009008107 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 363 |
| Number Of SNVs | 82 |
| Number Of Permutations | 16644 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.774 |
COSMIC
| Number Of Residues | 363 |
| Number Of SNVs | 4 |
| Number Of Permutations | 920 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.167 |
| p-value | 0.545 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
