General Structure Information
| PDB ID | 3l6b |
| HGNC Gene Label(s) | SRR |
| Structure Name | x-ray crystal structure of human serine racemase in complex with malonate a potent inhibitor |
| Resolution | 1.5Å |
| Reference | AUTH M.A.SMITH,V.MACK,A.EBNETH,I.MORAES,B.FELICETTI,M.WOOD,AUTH 2 D.SCHONFELD,O.MATHER,A.CESURA,J.BARKERTITL THE STRUCTURE OF MAMMALIAN SERINE RACEMASE: EVIDENCE FORTITL 2 CONFORMATIONAL CHANGES UPON INHIBITOR BINDING.REF J.BIOL.CHEM. V. 285 12873 2010REFN ISSN 0021-9258PMID 20106978DOI 10.1074/JBC.M109.050062 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 322 |
| Number Of SNVs | 65 |
| Number Of Permutations | 11405 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.131 |
| p-value | 0.156 |
COSMIC
| Number Of Residues | 322 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.488 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.254 |
| p-value | 0.647 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
