General Structure Information
| PDB ID | 3l6a |
| HGNC Gene Label(s) | EIF4G2 |
| Structure Name | crystal structure of the c-terminal region of human p97 |
| Resolution | 2.0Å |
| Reference | AUTH S.FAN,M.JIA,W.GONGTITL CRYSTAL STRUCTURE OF THE C-TERMINAL REGION OF HUMANTITL 2 P97/DAP5REF PROTEINS 2010REFN ESSN 1097-0134DOI 10.1002/PROT.22735 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 348 |
| Number Of SNVs | 73 |
| Number Of Permutations | 20605 |
| Optimal Distance Threshold | 30.0 |
| K Statistic | 0.449 |
| p-value | 0.452 |
COSMIC
| Number Of Residues | 348 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1481 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.3 |
| p-value | 0.502 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 73 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.203 |
| p-value | 0.679 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
