General Structure Information
| PDB ID | 3kq0 |
| HGNC Gene Label(s) | ORM1 |
| Structure Name | crystal structure of human alpha1-acid glycoprotein |
| Resolution | 1.8Å |
| Reference | AUTH D.L.SCHONFELD,R.B.RAVELLI,U.MUELLER,A.SKERRATITL THE 1.8-A CRYSTAL STRUCTURE OF ALPHA1-ACIDTITL 2 GLYCOPROTEIN (OROSOMUCOID) SOLVED BY UV RIP REVEALSTITL 3 THE BROAD DRUG-BINDING ACTIVITY OF THIS HUMANTITL 4 PLASMA LIPOCALIN.REF J.MOL.BIOL. V. 384 393 2008REFN ISSN 0022-2836PMID 18823996DOI 10.1016/J.JMB.2008.09.020 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 174 |
| Number Of SNVs | 38 |
| Number Of Permutations | 18050 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.083 |
| p-value | 0.491 |
COSMIC
| Number Of Residues | 174 |
| Number Of SNVs | 3 |
| Number Of Permutations | 249 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | 0.333 |
| p-value | 0.808 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 38 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | -0.257 |
| p-value | 0.717 |