General Structure Information
| PDB ID | 3kgr |
| HGNC Gene Label(s) | LAIR1 |
| Structure Name | crystal structure of the human leukocyte-associated ig-like receptor-1 (lair-1) |
| Resolution | 1.8Å |
| Reference | AUTH T.H.C.BRONDIJK,T.DE RUITER,J.BALLERING,H.WIENK,R.J.LEBBINK,AUTH 2 H.VAN INGEN,R.BOELENS,R.W.FARNDALE,L.MEYAARD,E.G.HUIZINGATITL CRYSTAL STRUCTURE AND COLLAGEN-BINDING SITE OF IMMUNETITL 2 INHIBITORY RECEPTOR LAIR-1: UNEXPECTED IMPLICATIONS FORTITL 3 COLLAGEN BINDING BY PLATELET RECEPTOR GPVIREF BLOOD V. 115 1364 2010REFN ISSN 0006-4971PMID 20007810DOI 10.1182/BLOOD-2009-10-246322 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 97 |
| Number Of SNVs | 39 |
| Number Of Permutations | 10241 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.305 |
| p-value | 0.112 |
COSMIC
| Number Of Residues | 97 |
| Number Of SNVs | 4 |
| Number Of Permutations | 92 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.167 |
| p-value | 0.367 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 39 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.172 |
| p-value | 0.572 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
