General Structure Information
| PDB ID | 3jwq |
| HGNC Gene Label(s) | PDE6C |
| Structure Name | crystal structure of chimeric pde5/pde6 catalytic domain complexed with sildenafil |
| Resolution | 2.87Å |
| Reference | AUTH B.BARREN,L.GAKHAR,H.MURADOV,K.K.BOYD,S.RAMASWAMY,AUTH 2 N.O.ARTEMYEVTITL STRUCTURAL BASIS OF PHOSPHODIESTERASE 6 INHIBITION BY THETITL 2 C-TERMINAL REGION OF THE GAMMA-SUBUNITREF EMBO J. V. 28 3613 2009REFN ISSN 0261-4189PMID 19798052DOI 10.1038/EMBOJ.2009.284 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 40 |
| Number Of SNVs | 5 |
| Number Of Permutations | 287 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.2 |
| p-value | 0.686 |