General Structure Information
| PDB ID | 3iu6 |
| HGNC Gene Label(s) | PBRM1 |
| Structure Name | crystal structure of the sixth bromodomain of human poly-bromodomain containing protein 1 (pb1) |
| Resolution | 1.79Å |
| Reference | AUTH P.FILIPPAKOPOULOS,S.PICAUD,M.MANGOS,T.KEATES,J.P.LAMBERT,AUTH 2 D.BARSYTE-LOVEJOY,I.FELLETAR,R.VOLKMER,S.MULLER,T.PAWSON,AUTH 3 A.C.GINGRAS,C.H.ARROWSMITH,S.KNAPPTITL HISTONE RECOGNITION AND LARGE-SCALE STRUCTURAL ANALYSIS OFTITL 2 THE HUMAN BROMODOMAIN FAMILY.REF CELL(CAMBRIDGE,MASS.) V. 149 214 2012REFN ISSN 0092-8674PMID 22464331DOI 10.1016/J.CELL.2012.02.013 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 141 |
| Number Of SNVs | 27 |
| Number Of Permutations | 13677 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.148 |
| p-value | 0.213 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
