3IT8.C | TNF

General Structure Information

PDB ID 3it8
HGNC Gene Label(s) TNF
Structure Name crystal structure of tnf alpha complexed with a poxvirus mhc-related tnf binding protein
Resolution 2.8Å
Reference AUTH Z.YANG,A.P.WEST JR.,P.J.BJORKMANTITL CRYSTAL STRUCTURE OF TNFA COMPLEXED WITH A POXVIRUSTITL 2 MHC-RELATED TNF BINDING PROTEINREF NAT.STRUCT.MOL.BIOL.REFN ESSN 1545-9985DOI 10.1038/NSMB.1683

Variant Set Distributions

ExAC Variants

Number Of Residues 152
Number Of SNVs 25
Number Of Permutations 4122
Optimal Distance Threshold 11.0
K Statistic 0.097
p-value 0.163

Mapped Variants

[+] ExAC Missense Variants