General Structure Information
| PDB ID | 3ii0 |
| HGNC Gene Label(s) | GOT1 |
| Structure Name | crystal structure of human glutamate oxaloacetate transaminase 1 (got1) |
| Resolution | 2.05Å |
| Reference | AUTH E.UGOCHUKWU,E.PILKA,C.COOPER,J.E.BRAY,W.W.YUE,J.MUNIZ,AUTH 2 A.CHAIKUAD,K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN GLUTAMATE OXALOACETATETITL 2 TRANSAMINASE 1 (GOT1)REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 399 |
| Number Of SNVs | 78 |
| Number Of Permutations | 39498 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.268 |
| p-value | 0.467 |
COSMIC
| Number Of Residues | 399 |
| Number Of SNVs | 7 |
| Number Of Permutations | 518 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.381 |
| p-value | 0.267 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 78 |
| Number Of COSMIC SNVs | 7 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.224 |
| p-value | 0.06 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
