General Structure Information
| PDB ID | 3gwx |
| HGNC Gene Label(s) | PPARD |
| Structure Name | molecular recognition of fatty acids by peroxisome proliferator-activated receptors |
| Resolution | 2.4Å |
| Reference | AUTH H.E.XU,M.H.LAMBERT,V.G.MONTANA,D.J.PARKS,AUTH 2 S.G.BLANCHARD,P.J.BROWN,D.D.STERNBACH,J.M.LEHMANN,AUTH 3 G.B.WISELY,T.M.WILLSON,S.A.KLIEWER,M.V.MILBURNTITL MOLECULAR RECOGNITION OF FATTY ACIDS BY PEROXISOMETITL 2 PROLIFERATOR-ACTIVATED RECEPTORS.REF MOL.CELL V. 3 397 1999REFN ISSN 1097-2765PMID 10198642DOI 10.1016/S1097-2765(00)80467-0 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 271 |
| Number Of SNVs | 50 |
| Number Of Permutations | 23254 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.016 |
| p-value | 0.147 |
COSMIC
| Number Of Residues | 271 |
| Number Of SNVs | 6 |
| Number Of Permutations | 3937 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.133 |
| p-value | 0.74 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 50 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | -0.054 |
| p-value | 0.813 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
