General Structure Information
| PDB ID | 3gub |
| HGNC Gene Label(s) | DAPK1 |
| Structure Name | crystal structure of dapkl93g complexed with n6-(2- phenylethyl)adenosine |
| Resolution | 1.71Å |
| Reference | AUTH L.K.MCNAMARA,J.S.SCHAVOCKY,D.M.WATTERSON,AUTH 2 J.S.BRUNZELLETITL CRYSTAL STRUCTURES OF THE DAPK GATEKEEPER MUTANTTITL 2 COMPLEXED WITH N6-MODIFIED ADENOSINE ANALOGS.REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 276 |
| Number Of SNVs | 55 |
| Number Of Permutations | 27443 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.237 |
| p-value | 0.2 |
COSMIC
| Number Of Residues | 276 |
| Number Of SNVs | 6 |
| Number Of Permutations | 2650 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.467 |
| p-value | 0.643 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 55 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.302 |
| p-value | 0.235 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
