General Structure Information
| PDB ID | 3ghg |
| HGNC Gene Label(s) | FGG |
| Structure Name | crystal structure of human fibrinogen |
| Resolution | 2.9Å |
| Reference | AUTH J.M.KOLLMAN,L.PANDI,M.R.SAWAYA,M.RILEY,R.F.DOOLITTLETITL CRYSTAL STRUCTURE OF HUMAN FIBRINOGEN.REF BIOCHEMISTRY V. 48 3877 2009REFN ISSN 0006-2960PMID 19296670DOI 10.1021/BI802205G |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 381 |
| Number Of SNVs | 79 |
| Number Of Permutations | 81529 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.118 |
| p-value | 0.679 |
ClinVar
| Number Of Residues | 381 |
| Number Of SNVs | 10 |
| Number Of Permutations | 15357 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.089 |
| p-value | 0.002 |
COSMIC
| Number Of Residues | 381 |
| Number Of SNVs | 7 |
| Number Of Permutations | 14733 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.286 |
| p-value | 0.315 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 79 |
| Number Of ClinVar SNVs | 10 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.078 |
| p-value | 0.006 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 79 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.068 |
| p-value | 0.921 |