General Structure Information
| PDB ID | 3g33 |
| HGNC Gene Label(s) | CDK4 |
| Structure Name | crystal structure of cdk4/cyclin d3 |
| Resolution | 3.0Å |
| Reference | AUTH T.TAKAKI,A.ECHALIER,N.R.BROWN,T.HUNT,J.A.ENDICOTT,M.E.NOBLETITL THE STRUCTURE OF CDK4/CYCLIN D3 HAS IMPLICATIONS FOR MODELSTITL 2 OF CDK ACTIVATION.REF PROC.NATL.ACAD.SCI.USA V. 106 4171 2009REFN ISSN 0027-8424PMID 19237555DOI 10.1073/PNAS.0809674106 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 291 |
| Number Of SNVs | 55 |
| Number Of Permutations | 9615 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.089 |
| p-value | 0.048 |
COSMIC
| Number Of Residues | 291 |
| Number Of SNVs | 4 |
| Number Of Permutations | 340 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.167 |
| p-value | 0.313 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
