3FRS.A | IST1

General Structure Information

PDB ID 3frs
HGNC Gene Label(s) IST1
Structure Name structure of human ist1(ntd) (residues 1-189)(p43212)
Resolution 2.61Å
Reference AUTH M.BAJOREK,H.L.SCHUBERT,J.MCCULLOUGH,C.LANGELIER,D.M.ECKERT,AUTH 2 W.M.STUBBLEFIELD,N.T.UTER,D.G.MYSZKA,C.P.HILL,W.I.SUNDQUISTTITL STRUCTURAL BASIS FOR ESCRT-III PROTEIN AUTOINHIBITION.REF NAT.STRUCT.MOL.BIOL. V. 16 754 2009REFN ISSN 1545-9993PMID 19525971DOI 10.1038/NSMB.1621

Variant Set Distributions

ExAC Variants

Number Of Residues 175
Number Of SNVs 39
Number Of Permutations 7275
Optimal Distance Threshold 7.0
K Statistic 0.031
p-value 0.22

Mapped Variants

[+] ExAC Missense Variants