General Structure Information
| PDB ID | 3fd5 |
| HGNC Gene Label(s) | SEPHS1 |
| Structure Name | crystal structure of human selenophosphate synthetase 1 complex with ampcp |
| Resolution | 1.9Å |
| Reference | AUTH K.T.WANG,J.WANG,L.F.LI,X.D.SUTITL CRYSTAL STRUCTURES OF CATALYTIC INTERMEDIATES OFTITL 2 HUMAN SELENOPHOSPHATE SYNTHETASE 1.REF J.MOL.BIOL. V. 390 747 2009REFN ISSN 0022-2836PMID 19477186DOI 10.1016/J.JMB.2009.05.032 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 339 |
| Number Of SNVs | 47 |
| Number Of Permutations | 7570 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.003 |
| p-value | 0.285 |
COSMIC
| Number Of Residues | 339 |
| Number Of SNVs | 5 |
| Number Of Permutations | 181 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.2 |
| p-value | 0.174 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 47 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 23.0 |
| K Statistic | -0.389 |
| p-value | 0.265 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
