General Structure Information
| PDB ID | 3fcx |
| HGNC Gene Label(s) | ESD |
| Structure Name | crystal structure of human esterase d |
| Resolution | 1.5Å |
| Reference | AUTH D.WU,Y.LI,G.SONG,D.ZHANG,N.SHAW,Z.J.LIUTITL CRYSTAL STRUCTURE OF HUMAN ESTERASE D: A POTENTIALTITL 2 GENETIC MARKER OF RETINOBLASTOMAREF FASEB J. V. 23 1441 2009REFN ISSN 0892-6638PMID 19126594DOI 10.1096/FJ.08-125286 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 268 |
| Number Of SNVs | 67 |
| Number Of Permutations | 6767 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.014 |
| p-value | 0.988 |
COSMIC
| Number Of Residues | 268 |
| Number Of SNVs | 5 |
| Number Of Permutations | 558 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.5 |
| p-value | 0.832 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 67 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | -0.05 |
| p-value | 0.824 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
