General Structure Information
| PDB ID | 3f3y |
| HGNC Gene Label(s) | SULT2A1 |
| Structure Name | crystal structure of human cytosolic sulfotransferase sult2a1 in complex with pap and lithocholic acid |
| Resolution | 2.2Å |
| Reference | AUTH P.W.PAN,A.DONG,M.AMAYA,A.M.EDWARDSTITL RYSTAL STRUCTURE OF HUMAN CYTOSOLICTITL 2 SULFOTRANSFERASE SULT2A1 IN COMPLEX WITH PAP ANDTITL 3 LITHOCHOLIC ACIDREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 282 |
| Number Of SNVs | 76 |
| Number Of Permutations | 23403 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.089 |
| p-value | 0.243 |
COSMIC
| Number Of Residues | 282 |
| Number Of SNVs | 6 |
| Number Of Permutations | 400 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.2 |
| p-value | 0.642 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 76 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.087 |
| p-value | 0.805 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
