General Structure Information
| PDB ID | 3f3s |
| HGNC Gene Label(s) | CRYL1 |
| Structure Name | the crystal structure of human lambda-crystallin, cryl1 |
| Resolution | 2.0Å |
| Reference | AUTH E.UGOCHUKWU,C.JOHANSSON,W.W.YUE,G.KOCHAN,E.PILKA,A.KRAMM,AUTH 2 A.C.W.PIKE,P.FILIPPAKOPOULOS,F.VON DELFT,U.OPPERMANNTITL THE CRYSTAL STRUCTURE OF HUMAN LAMBDA-CRYSTALLIN, CRYL1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 311 |
| Number Of SNVs | 83 |
| Number Of Permutations | 15104 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.017 |
| p-value | 0.489 |
COSMIC
| Number Of Residues | 311 |
| Number Of SNVs | 4 |
| Number Of Permutations | 1446 |
| Optimal Distance Threshold | 32.0 |
| K Statistic | 0.833 |
| p-value | 0.975 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 83 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.393 |
| p-value | 0.391 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
