General Structure Information
| PDB ID | 3efh |
| HGNC Gene Label(s) | PRPS1 |
| Structure Name | crystal structure of human phosphoribosyl pyrophosphate synthetase 1 |
| Resolution | 2.6Å |
| Reference | AUTH X.PENG,X.LITITL CRYSTAL STRUCTURE OF HUMAN PHOSPHORIBOSYLTITL 2 PYROPHOSPHATE SYNTHETASE 1REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 307 |
| Number Of SNVs | 7 |
| Number Of Permutations | 3457 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.19 |
| p-value | 0.407 |
ClinVar
| Number Of Residues | 307 |
| Number Of SNVs | 17 |
| Number Of Permutations | 9786 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.176 |
| p-value | 0.501 |
COSMIC
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 7 |
| Number Of ClinVar SNVs | 17 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.092 |
| p-value | 0.524 |
Cosmic vs. ExAC
