General Structure Information
| PDB ID | 3dlq |
| HGNC Gene Label(s) | IL22 |
| Structure Name | crystal structure of the il-22/il-22r1 complex |
| Resolution | 1.9Å |
| Reference | AUTH L.BLEICHER,P.R.DE MOURA,L.WATANABE,D.COLAU,AUTH 2 L.DUMOUTIER,J.-C.RENAULD,I.POLIKARPOVTITL CRYSTAL STRUCTURE OF THE IL-22/IL-22R1 COMPLEX ANDTITL 2 ITS IMPLICATIONS FOR THE IL-22 SIGNALING MECHANISMREF FEBS LETT. V. 582 2985 2008REFN ISSN 0014-5793PMID 18675809DOI 10.1016/J.FEBSLET.2008.07.046 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 131 |
| Number Of SNVs | 34 |
| Number Of Permutations | 2043 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.039 |
| p-value | 0.934 |
COSMIC
| Number Of Residues | 131 |
| Number Of SNVs | 4 |
| Number Of Permutations | 118 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.333 |
| p-value | 0.802 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 34 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | -0.114 |
| p-value | 0.752 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
