General Structure Information
| PDB ID | 3cxl |
| HGNC Gene Label(s) | CHN1 |
| Structure Name | crystal structure of human chimerin 1 (chn1) |
| Resolution | 2.6Å |
| Reference | AUTH L.SHEN,M.BUCK,Y.TONG,W.TEMPEL,F.MACKENZIE,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,M.WILKSTROM,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN CHIMERIN 1 (CHN1).REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 401 |
| Number Of SNVs | 75 |
| Number Of Permutations | 22015 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.209 |
| p-value | 0.388 |
ClinVar
| Number Of Residues | 401 |
| Number Of SNVs | 7 |
| Number Of Permutations | 1663 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.81 |
| p-value | 0.005 |
COSMIC
| Number Of Residues | 401 |
| Number Of SNVs | 5 |
| Number Of Permutations | 544 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.1 |
| p-value | 0.811 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of ClinVar SNVs | 7 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | 0.382 |
| p-value | 0.003 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 75 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 36.0 |
| K Statistic | 0.269 |
| p-value | 0.808 |