General Structure Information
| PDB ID | 3c5h |
| HGNC Gene Label(s) | ARHGAP35 |
| Structure Name | crystal structure of the ras homolog domain of human grlf1 (p190rhogap) |
| Resolution | 1.8Å |
| Reference | AUTH L.SHEN,Y.TONG,W.TEMPEL,F.MACKENZIE,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RAS HOMOLOG DOMAIN OFTITL 2 HUMAN GRLF1 (P190RHOGAP).REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 224 |
| Number Of SNVs | 24 |
| Number Of Permutations | 7489 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.036 |
| p-value | 0.173 |
COSMIC
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 24 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.286 |
| p-value | 0.396 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
