General Structure Information
| PDB ID | 3bpo |
| HGNC Gene Label(s) | IL4R |
| Structure Name | crystal structure of the il13-il4r-il13ra ternary complex |
| Resolution | 3.0Å |
| Reference | AUTH S.L.LAPORTE,Z.S.JUO,J.VACLAVIKOVA,L.A.COLF,X.QI,N.M.HELLER,AUTH 2 A.D.KEEGAN,K.C.GARCIATITL MOLECULAR AND STRUCTURAL BASIS OF CYTOKINE RECEPTORTITL 2 PLEIOTROPY IN THE INTERLEUKIN-4/13 SYSTEM.REF CELL(CAMBRIDGE,MASS.) V. 132 259 2008REFN ISSN 0092-8674PMID 18243101DOI 10.1016/J.CELL.2007.12.030 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 195 |
| Number Of SNVs | 59 |
| Number Of Permutations | 12689 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.372 |
| p-value | 0.494 |
COSMIC
| Number Of Residues | 195 |
| Number Of SNVs | 6 |
| Number Of Permutations | 997 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.067 |
| p-value | 0.769 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 59 |
| Number Of COSMIC SNVs | 6 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | -0.084 |
| p-value | 0.683 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
