General Structure Information
| PDB ID | 3bhm |
| HGNC Gene Label(s) | CBR1 |
| Structure Name | crystal structure of human carbonyl reductase 1 in complex with s-hydroxymethylglutathione |
| Resolution | 1.8Å |
| Reference | AUTH R.L.BATEMAN,D.RAUH,B.TAVSHANJIAN,K.M.SHOKATTITL HUMAN CARBONYL REDUCTASE 1 IS ANTITL 2 S-NITROSOGLUTATHIONE REDUCTASEREF J.BIOL.CHEM. V. 283 35756 2008REFN ISSN 0021-9258PMID 18826943DOI 10.1074/JBC.M807125200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 274 |
| Number Of SNVs | 88 |
| Number Of Permutations | 30475 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.02 |
| p-value | 0.652 |
COSMIC
| Number Of Residues | 274 |
| Number Of SNVs | 4 |
| Number Of Permutations | 494 |
| Optimal Distance Threshold | 10.0 |
| K Statistic | 0.333 |
| p-value | 0.134 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 88 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.237 |
| p-value | 0.797 |