General Structure Information
| PDB ID | 3bd9 |
| HGNC Gene Label(s) | HS3ST5 |
| Structure Name | human 3-o-sulfotransferase isoform 5 with bound pap |
| Resolution | 2.3Å |
| Reference | AUTH D.XU,A.F.MOON,D.SONG,L.C.PEDERSEN,J.LIUTITL ENGINEERING SULFOTRANSFERASES TO MODIFY HEPARANTITL 2 SULFATE.REF NAT.CHEM.BIOL. V. 4 200 2008REFN ISSN 1552-4450PMID 18223645DOI 10.1038/NCHEMBIO.66 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 255 |
| Number Of SNVs | 55 |
| Number Of Permutations | 9374 |
| Optimal Distance Threshold | 9.0 |
| K Statistic | 0.035 |
| p-value | 0.042 |
COSMIC
| Number Of Residues | 255 |
| Number Of SNVs | 6 |
| Number Of Permutations | 38 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | 0.2 |
| p-value | 0.43 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 55 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 19.0 |
| K Statistic | -0.275 |
| p-value | 1.0 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
