General Structure Information
| PDB ID | 3bd0 |
| HGNC Gene Label(s) | MEMO1 |
| Structure Name | crystal structure of memo, form ii |
| Resolution | 3.01Å |
| Reference | AUTH C.QIU,S.LIENHARD,N.E.HYNES,A.BADACHE,D.J.LEAHYTITL MEMO IS HOMOLOGOUS TO NONHEME IRON DIOXYGENASESTITL 2 AND BINDS AN ERBB2-DERIVED PHOSPHOPEPTIDE IN ITSTITL 3 VESTIGIAL ACTIVE SITE.REF J.BIOL.CHEM. V. 283 2734 2008REFN ISSN 0021-9258PMID 18045866DOI 10.1074/JBC.M703523200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 293 |
| Number Of SNVs | 33 |
| Number Of Permutations | 12764 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.011 |
| p-value | 0.887 |
COSMIC
| Number Of Residues | 293 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 24.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 33 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.14 |
| p-value | 0.904 |