General Structure Information
| PDB ID | 3bch |
| HGNC Gene Label(s) | RPSA |
| Structure Name | crystal structure of the human laminin receptor precursor |
| Resolution | 2.15Å |
| Reference | AUTH K.V.JAMIESON,J.WU,S.R.HUBBARD,D.MERUELOTITL CRYSTAL STRUCTURE OF THE HUMAN LAMININ RECEPTORTITL 2 PRECURSOR.REF J.BIOL.CHEM. V. 283 3002 2008REFN ISSN 0021-9258PMID 18063583DOI 10.1074/JBC.C700206200 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 197 |
| Number Of SNVs | 17 |
| Number Of Permutations | 7561 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.081 |
| p-value | 0.065 |
ClinVar
| Number Of Residues | 197 |
| Number Of SNVs | 4 |
| Number Of Permutations | 742 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.833 |
| p-value | 0.044 |
COSMIC
| Number Of Residues | 197 |
| Number Of SNVs | 3 |
| Number Of Permutations | 46 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.502 |
| p-value | 0.261 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 17 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | -0.387 |
| p-value | 0.549 |
Pathogenic Proximity Analysis
ClinVar PathProx Analysis
COSMIC PathProx Analysis
