3B6U.A | KIF3B

General Structure Information

PDB ID 3b6u
HGNC Gene Label(s) KIF3B
Structure Name crystal structure of the motor domain of human kinesin family member 3b in complex with adp
Resolution 1.8Å
Reference AUTH H.ZHU,Y.SHEN,W.TEMPEL,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL MOTOR DOMAIN OF HUMAN KINESIN FAMILY MEMBER 3B INTITL 2 COMPLEX WITH ADP.REF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 323
Number Of SNVs 57
Number Of Permutations 32223
Optimal Distance Threshold 6.0
K Statistic 0.013
p-value 0.929
COSMIC

Number Of Residues 323
Number Of SNVs 5
Number Of Permutations 187
Optimal Distance Threshold 19.0
K Statistic 0.2
p-value 0.932

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Number Of ExAC SNVs 57
Number Of COSMIC SNVs 5
Optimal Distance Threshold 14.0
K Statistic -0.134
p-value 0.75

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants