General Structure Information
| PDB ID | 2ysq |
| HGNC Gene Label(s) | ARHGEF9 |
| Structure Name | solution structure of the sh3 domain from rho guanine nucleotide exchange factor 9 |
| Resolution | -1.0Å |
| Reference | AUTH X.R.QIN,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN FROM RHOTITL 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR 9REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 69 |
| Number Of SNVs | 3 |
| Number Of Permutations | 75 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.667 |
| p-value | 0.385 |
COSMIC
| Number Of Residues | 69 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 3 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | -0.667 |
| p-value | 0.6 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
