General Structure Information
| PDB ID | 2yn8 |
| HGNC Gene Label(s) | EPHB4 |
| Structure Name | ephb4 kinase domain inhibitor complex |
| Resolution | 2.11Å |
| Reference | AUTH R.C.OVERMAN,I.GREEN,C.M.TRUMAN,J.A.READ,K.J.EMBREY,AUTH 2 M.S.B.MCALISTER,T.K.ATTWOODTITL STABILITY AND SOLUBILITY ENGINEERING OF THE EPHB4 TYROSINETITL 2 KINASE CATALYTIC DOMAIN USING A RATIONALLY DESIGNEDTITL 3 SYNTHETIC LIBRARY.REF PROTEIN ENG.DES.SEL. V. 26 695 2013REFN ISSN 1741-0126PMID 23840071DOI 10.1093/PROTEIN/GZT032 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 253 |
| Number Of SNVs | 52 |
| Number Of Permutations | 6801 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.226 |
| p-value | 0.022 |