2YLE.A | SPIRE1

General Structure Information

PDB ID 2yle
HGNC Gene Label(s) SPIRE1
Structure Name crystal structure of the human spir-1 kind fsi domain in complex with the fsi peptide
Resolution 1.8Å
Reference AUTH K.ZETH,M.PECHLIVANIS,A.SAMOL,S.PLEISER,C.VONRHEIN,AUTH 2 E.KERKHOFFTITL MOLECULAR BASIS OF ACTIN NUCLEATION FACTOR COOPERATIVITY:TITL 2 CRYSTAL STRUCTURE OF THE SPIR-1 KINASE NON-CATALYTIC C-LOBETITL 3 DOMAIN (KIND)FORMIN-2 FORMIN SPIR INTERACTION MOTIF (FSI)TITL 4 COMPLEX.REF J.BIOL.CHEM. V. 286 30732 2011REFN ISSN 0021-9258PMID 21705804DOI 10.1074/JBC.M111.257782

Variant Set Distributions

ExAC Variants

Number Of Residues 169
Number Of SNVs 23
Number Of Permutations 2944
Optimal Distance Threshold 12.0
K Statistic 0.13
p-value 0.814

Mapped Variants

[+] ExAC Missense Variants