2YHO.C | MYLIP

General Structure Information

PDB ID 2yho
HGNC Gene Label(s) MYLIP
Structure Name the idol-ube2d complex mediates sterol-dependent degradation of the ldl receptor
Resolution 2.1Å
Reference AUTH L.ZHANG,L.FAIRALL,B.T.GOULT,A.C.CALKIN,C.HONG,C.J.MILLARD,AUTH 2 P.TONTONOZ,J.W.SCHWABETITL THE IDOL-UBE2D COMPLEX MEDIATES STEROL-DEPENDENTTITL 2 DEGRADATION OF THE LDL RECEPTOR.REF GENES DEV. V. 25 1262 2011REFN ISSN 0890-9369PMID 21685362DOI 10.1101/GAD.2056211

Variant Set Distributions

ExAC Variants

Number Of Residues 67
Number Of SNVs 22
Number Of Permutations 9714
Optimal Distance Threshold 5.0
K Statistic 0.052
p-value 0.693

Mapped Variants

[+] ExAC Missense Variants