General Structure Information
| PDB ID | 2ygq |
| HGNC Gene Label(s) | WIF1 |
| Structure Name | wif domain-epidermal growth factor (egf)-like domains 1-3 of human wnt inhibitory factor 1 in complex with 1,2-dipalmitoylphosphatidylcholine |
| Resolution | 3.95Å |
| Reference | AUTH T.MALINAUSKAS,A.R.ARICESCU,W.LU,C.SIEBOLD,E.Y.JONESTITL MODULAR MECHANISM OF WNT SIGNALING INHIBITION BY WNTTITL 2 INHIBITORY FACTOR 1REF NAT.STRUCT.MOL.BIOL. V. 18 886 2011REFN ISSN 1545-9993PMID 21743455DOI 10.1038/NSMB.2081 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 240 |
| Number Of SNVs | 61 |
| Number Of Permutations | 26369 |
| Optimal Distance Threshold | 8.0 |
| K Statistic | 0.044 |
| p-value | 0.532 |
COSMIC
| Number Of Residues | 240 |
| Number Of SNVs | 5 |
| Number Of Permutations | 101 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.2 |
| p-value | 0.077 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 61 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 21.0 |
| K Statistic | 0.63 |
| p-value | 0.053 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
