General Structure Information
| PDB ID | 2yd9 |
| HGNC Gene Label(s) | PTPRS |
| Structure Name | crystal structure of the n-terminal ig1-3 module of human receptor protein tyrosine phosphatase sigma |
| Resolution | 2.6Å |
| Reference | AUTH C.H.COLES,Y.SHEN,A.P.TENNEY,C.SIEBOLD,G.C.SUTTON,W.LU,AUTH 2 J.T.GALLAGHER,E.Y.JONES,J.G.FLANAGAN,A.R.ARICESCUTITL PROTEOGLYCAN-SPECIFIC MOLECULAR SWITCH FOR RPTP SIGMATITL 2 CLUSTERING AND NEURONAL EXTENSION.REF SCIENCE V. 332 484 2011REFN ISSN 0036-8075PMID 21454754DOI 10.1126/SCIENCE.1200840 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 278 |
| Number Of SNVs | 45 |
| Number Of Permutations | 43957 |
| Optimal Distance Threshold | 7.0 |
| K Statistic | 0.017 |
| p-value | 0.063 |
COSMIC
| Number Of Residues | 278 |
| Number Of SNVs | 4 |
| Number Of Permutations | 416 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.333 |
| p-value | 0.131 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
