2YCU.A | MYH14

General Structure Information

PDB ID 2ycu
HGNC Gene Label(s) MYH14
Structure Name crystal structure of human non muscle myosin 2c in pre-power stroke state
Resolution 2.25Å
Reference AUTH K.CHINTHALAPUDI,S.M.HEISSLER,D.J.MANSTEINTITL CRYSTAL STRUCTURE OF HUMAN NON MUSCLE MYOSIN 2C INTITL 2 PRE-POWER STROKE STATEREF TO BE PUBLISHEDREFN

Variant Set Distributions

ExAC Variants

Number Of Residues 737
Number Of SNVs 163
Number Of Permutations 50980
Optimal Distance Threshold 34.0
K Statistic 0.394
p-value 0.057
ClinVar

Number Of Residues 737
Number Of SNVs 3
Number Of Permutations 402
Optimal Distance Threshold 12.0
K Statistic 0.333
p-value 0.458
COSMIC

Number Of Residues 737
Number Of SNVs 6
Number Of Permutations 984
Optimal Distance Threshold 23.0
K Statistic 0.067
p-value 0.583

Ripley’s K Analysis Plots

ExACClinVarCOSMIC

Variant Set Comparisons

ClinVar vs. ExAC

Number Of ExAC SNVs 163
Number Of ClinVar SNVs 3
Optimal Distance Threshold 12.0
K Statistic 0.296
p-value 0.383
Cosmic vs. ExAC

Number Of ExAC SNVs 163
Number Of COSMIC SNVs 8
Optimal Distance Threshold 21.0
K Statistic -0.111
p-value 0.83

Mapped Variants

[+] ExAC Missense Variants

[+] ClinVar Missense Variants

[+] COSMIC Missense Variants

Related Entries
2WTK|STRADA,CAB39,STK11
3F5N|SERPINI1
2WTK|STRADA,CAB39,STK11