General Structure Information
| PDB ID | 2y7j |
| HGNC Gene Label(s) | PHKG2 |
| Structure Name | structure of human phosphorylase kinase, gamma 2 |
| Resolution | 2.5Å |
| Reference | AUTH J.R.C.MUNIZ,A.SHRESTHA,P.SAVITSKY,J.WANG,P.RELLOS,O.FEDOROV,AUTH 2 N.BURGESS-BROWN,B.BRENNER,G.BERRIDGE,J.M.ELKINS,T.KROJER,AUTH 3 M.VOLLMAR,K.H.CHE,F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 4 J.WEIGELT,C.BOUNTRA,S.KNAPPTITL STRUCTURE OF HUMAN PHOSPHORYLASE KINASE, GAMMA 2REF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 281 |
| Number Of SNVs | 65 |
| Number Of Permutations | 31011 |
| Optimal Distance Threshold | 17.0 |
| K Statistic | 0.163 |
| p-value | 0.0 |
ClinVar
| Number Of Residues | 281 |
| Number Of SNVs | 4 |
| Number Of Permutations | 764 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.0 |
| p-value | 0.467 |
COSMIC
| Number Of Residues | 281 |
| Number Of SNVs | 3 |
| Number Of Permutations | 67 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | -0.144 |
| p-value | 0.68 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 65 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.558 |
| p-value | 0.069 |