General Structure Information
| PDB ID | 2x4d |
| HGNC Gene Label(s) | LHPP |
| Structure Name | crystal structure of human phospholysine phosphohistidine inorganic pyrophosphate phosphatase lhpp |
| Resolution | 1.92Å |
| Reference | AUTH M.VOLLMAR,C.GILEADI,K.GUO,P.SAVITSKY,J.R.C.MUNIZ,W.YUE,AUTH 2 C.ALLERSTON,F.VON DELFT,C.BOUNTRA,C.H.ARROWSMITH,J.WEIGELT,AUTH 3 A.EDWARDS,K.L.KAVANAGH,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN PHOSPHOLYSINE PHOSPHOHISTIDINETITL 2 INORGANIC PYROPHOSPHATE PHOSPHATASE LHPPREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 213 |
| Number Of SNVs | 69 |
| Number Of Permutations | 9859 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.119 |
| p-value | 0.094 |
COSMIC
| Number Of Residues | 213 |
| Number Of SNVs | 5 |
| Number Of Permutations | 578 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.1 |
| p-value | 0.901 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 69 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.256 |
| p-value | 0.683 |