General Structure Information
| PDB ID | 2×47 |
| HGNC Gene Label(s) | MACROD1 |
| Structure Name | crystal structure of human macrod1 |
| Resolution | 1.7Å |
| Reference | AUTH D.CHEN,M.VOLLMAR,M.N.ROSSI,C.PHILLIPS,R.KRAEHENBUEHL,AUTH 2 D.SLADE,P.V.MEHROTRA,F.VON DELFT,S.K.CROSTHWAITE,O.GILEADI,AUTH 3 J.M.DENU,I.AHELTITL IDENTIFICATION OF MACRO DOMAIN PROTEINS AS NOVEL O-TITL 2 ACETYL-ADP-RIBOSE DEACETYLASES.REF J.BIOL.CHEM. V. 286 13261 2011REFN ISSN 0021-9258PMID 21257746DOI 10.1074/JBC.M110.206771 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 229 |
| Number Of SNVs | 64 |
| Number Of Permutations | 26183 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.139 |
| p-value | 0.26 |
COSMIC
| Number Of Residues | 229 |
| Number Of SNVs | 4 |
| Number Of Permutations | 44 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.167 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 64 |
| Number Of COSMIC SNVs | 4 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | -0.318 |
| p-value | 0.322 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
