General Structure Information
| PDB ID | 2wqm |
| HGNC Gene Label(s) | NEK7 |
| Structure Name | structure of apo human nek7 |
| Resolution | 2.1Å |
| Reference | AUTH M.W.RICHARDS,L.OREGAN,C.MAS-DROUX,J.M.Y.BLOT,AUTH 2 J.CHEUNG,S.HOELDER,A.M.FRY,R.BAYLISSTITL AN AUTO-INHIBITORY TYROSINE MOTIF IN THE CELL-TITL 2 CYCLE REGULATED NEK7 KINASE IS RELEASED THROUGHTITL 3 BINDING OF NEK9REF MOL.CELL V. 36 560 2009REFN ISSN 1097-2765PMID 19941817DOI 10.1016/J.MOLCEL.2009.09.038 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 258 |
| Number Of SNVs | 43 |
| Number Of Permutations | 21926 |
| Optimal Distance Threshold | 18.0 |
| K Statistic | 0.227 |
| p-value | 0.219 |
COSMIC
| Number Of Residues | 258 |
| Number Of SNVs | 3 |
| Number Of Permutations | 1 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 43 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 22.0 |
| K Statistic | 0.334 |
| p-value | 0.484 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
