General Structure Information
| PDB ID | 2wpi |
| HGNC Gene Label(s) | F9 |
| Structure Name | factor ixa superactive double mutant |
| Resolution | 1.99Å |
| Reference | AUTH T.ZOGG,H.BRANDSTETTERTITL STRUCTURAL BASIS OF THE COFACTOR- ANDTITL 2 SUBSTRATE-ASSISTED ACTIVATION OF HUMAN COAGULATIONTITL 3 FACTOR IXAREF STRUCTURE V. 17 1669 2009REFN ISSN 0969-2126PMID 20004170DOI 10.1016/J.STR.2009.10.011 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 59 |
| Number Of SNVs | 4 |
| Number Of Permutations | 755 |
| Optimal Distance Threshold | 11.0 |
| K Statistic | 0.0 |
| p-value | 0.415 |
ClinVar
| Number Of Residues | 59 |
| Number Of SNVs | 4 |
| Number Of Permutations | 755 |
| Optimal Distance Threshold | 14.0 |
| K Statistic | 0.0 |
| p-value | 0.07 |
COSMIC
| Number Of Residues | 59 |
| Number Of SNVs | 3 |
| Number Of Permutations | 27 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.333 |
| p-value | 1.0 |
Ripley’s K Analysis Plots
ExACClinVarCOSMIC
Variant Set Comparisons
ClinVar vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of ClinVar SNVs | 4 |
| Optimal Distance Threshold | 5.0 |
| K Statistic | 0.0 |
| p-value | 1.0 |
Cosmic vs. ExAC
| Number Of ExAC SNVs | 4 |
| Number Of COSMIC SNVs | 3 |
| Optimal Distance Threshold | 12.0 |
| K Statistic | 0.167 |
| p-value | 0.744 |